TAKE-HOME MESSAGE This best evidence consensus statement aimed to examine the relationship between centric occlusion (CO) and maximal intercuspation position (MIP) and the use of either as a treatment position for complete mouth rehabilitations in dentate or partially dentate patients. A total of 313 articles contributed to this review, finding that CO and MIP are not coincident in a majority of the population. With regard to complete mouth rehabilitation, most reports suggest that CO provides a physiologic, reliable, and reproducible position, with limited reports finding an association between TMJ symptomatology and CO-MIP discrepancies in the treated dentition. While CO-MIP discrepancies are the norm in the natural dentition, complete rehabilitations seem to perform better at CO rather than MIP based on available evidence. It should be noted that the authors could not include lower-quality evidence supporting the use of MIP as the treatm...
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